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Magnetic Beads for Reflux?
Gastroesophageal reflux disease (GERD) is considered to be a structural disorder. Usually the problem lies in the lower esophageal sphincter, that in certain patients is a little too loose at times, sending acidic stomach contents back up into the esophagus. The disease can lead to painful erosive esophagitis, or even serious conditions such as esophageal cancer.
A new clinical trial for the LINX Reflux Management System, a product of Torax Medical, Inc. (Shoreview, MN), is being conducted at selected U.S. and European centers. The device, described as a "bracelet" around the Lower Esophageal Sphincter composed of a series of miniature magnetic beads, can be implanted laparoscopically.
One of the hospitals in the United States, the UC San Diego Medical Center, is now actively participating in this early trial, as its press release testifies:
During a 20-30 minute minimally invasive surgical procedure, the device, made up of a series of magnetic beads, is secured around the bottom of the esophagus. Once in place, the magnetic attraction between the beads supports the valve to protect the esophagus from reflux, while still allowing it to open during swallowing or to release gas. Made of permanent rare earth magnets encased in titanium, the band is sized to fit each patient.
"With medical therapy alone, the production of acid in the stomach is suppressed, but the actual problem of reflux remains. The most appropriate long-term therapy for GERD is to restore the body's physiological barrier to correct the cause of reflux itself," said Horgan, the first surgeon in the western United States to implant the device in this clinical trial.
"I decided to participate in this clinical trial surgery because it may be a permanent, structural way of addressing the problem," said Gina Levine, age 43, who has suffered from GERD for more than 18 years. "I like the minimally invasive approach to this procedure and that it can be reversed if necessary."
And here's the information about the procedure, from a Torax Medical website:
The LINX™ procedure is performed by a surgeon using a minimally invasive surgical technique, called laparoscopy. The device is placed around the distal esophagus, just above the stomach, in the area of the Lower Esophageal Sphincter (LES).
Once the device is placed it will begin working immediately; magnetic attraction between the beads helps to keep the lower esophageal sphincter closed to prevent reflux, but will open to allow swallowing or the release of higher gastric pressures.
Following the procedure, under physician guidance, patients should be able to resume normal diet and will typically resume normal activities in less than a week.
Our guess is that the device will have to significantly outperform currently available therapies, such as open and Nissen fundoplications, before it is approved. But given the limited surgical therapeutic options nowadays, we really hope that the LINX Reflux Management System makes it through the trials and onto the surgical field.
For now, an empty trial page at ClinicalTrials.gov...
Product page: LINX™ REFLUX MANAGEMENT SYSTEM...
New Negative Pressure Wound Care Device from Smith & Nephew
At the ongoing American Academy of Orthopaedic Surgeons Annual Meeting in Las Vegas, Smith & Nephew has just introduced a new negative pressure wound therapy system called RENASYS EZ.
Features and functions according to the manufacturer:
In addition to a simple control that varies pressure from 40 to 200 mmHg and the ability to use both foam and gauze dressings, Smith & Nephew designed RENASYS EZ with additional features that enhance the patient experience and facilitate its ease of use.An intuitive design and quick-click connectors can help reduce the risk of error. Multiple safety alarms and a patient lock-out feature alert clinicians to changes in pressure status or pump function. The RENASYS EZ battery runs for up to 40 hours and charges in three hours. A convenient IV pole and bed mounts reduce the system's footprint at the patient's bedside. The system weighs only 7.4 lbs, reducing stress on the caregiver.
Press release: Smith & Nephew announce the new RENASYS EZ system for Negative Pressure Wound Therapy ...
DIY Culture Now Encompasses Home Made Prosthesis
A Tasmanian man, who lost his arm in a car accident, was told that he is a poor candidate for a prosthetic, since the amputation is too high for conventional devices. Being a rebel Aussie, Mark Lesek ignored the advice, and traveled to Sweden to implant a metal rod into his shoulder that can support a new prosthesis. The arm that he is now happily wearing is one he built with help from a business partner, and the project has developed further to include the University of Tasmania bioengineering team. The next step is to involve researchers that can help with lightening the unit using carbon fiber, and to create brain-computer interface to make the arm semi-autonomous.
More from The Mercury out of Hobart, Tasmania...
(hat tip: Gizmodo)
MAKO Introduces RIO Robotic Arm for Orthopedic Surgeries
MAKO Surgical has announced the release of its RIO Robotic Arm Interactive Orthopedic System. On display at this week's American Academy of Orthopaedic Surgeons annual meeting in Las Vegas, the device is designed to assist surgeons during knee resurfacing operation, a minimally invasive type of surgery thought to be useful for younger, active patients with early osteoarthritis. Since the knee resurfacing is a notoriously difficult operation to perform, the hope is that such a robot will introduce stability and precision.
From MAKO's press release:
The RIO™ Robotic Arm Interactive Orthopedic System and the RESTORIS® MCK MultiCompartmental Knee System make bone and tissue sparing MAKOplasty® partial knee resurfacing available to a larger population of patients. Previously, it was only possible to perform this precision resurfacing surgery on the medial (inner) portion of the knee. Now it can be performed on the medial, patellofemoral (top) or both components of the knee, offering a large and growing population of patients with early to mid-stage osteoarthritis (OA) of the knee a less invasive treatment option than total knee replacement.“The field of medical robotics is coming of age, and MAKO is committed to leading the way in orthopedic surgery,” said Dr. Maurice R. Ferré, President, Chief Executive Officer and Chairman of the MAKO Board of Directors. “The advancement of our technology with RIO™ and RESTORIS® MCK allows a greater number of patients with osteoarthritis to benefit from the precision and improved outcomes of MAKOplasty®. ”
MAKO’s robotic arm system is the first FDA-cleared robotic arm system for orthopedic surgery. It provides patient-specific, three-dimensional modeling for pre-surgical planning. As surgeons use the robotic arm to resurface the knee for placement of the implants, RIO™ provides real-time inter-operative visual, tactile and auditory feedback, enabling a high level of precision and optimal positioning of the implants.
MAKOplasty® provides the potential for improved surgical outcomes, with a less invasive partial knee resurfacing procedure that spares healthy bone and tissue, preserves ligaments and allows for a more rapid recovery and a more natural feeling knee.
More from the product factsheet:
Accurately plan implant size, orientation and alignment using CT-derived 3-D modelingPress release: MAKO Surgical Corp. Expands MAKOplasty® Partial Knee Resurfacing Capabilities with Next Generation Robotic Arm and ImplantsCapture the pre-resection patient-specific kinematics through full flexion and extension
Make real-time intra-operative adjustments to correct knee kinematics and soft-tissue balance
What makes the MAKOplasty® procedure powered by RIO™ unique?
Tissue and bone sparing, with minimal trauma for faster recovery
Patient and anatomy specific planning for ideal implant placement to restore natural knee kinematics
Tactile technology with 3-D visualization for controlled resurfacing within the pre-defined portions of the knee
Eliminates the need for conventional, invasive instrumentation
Performed through a small, minimal incision
RIO™ assists surgeon in optimizing implant position and alignment
Minimal soft tissue retraction required for cutting tool only
Pre-resection joint balancing and limb alignment
Thoracic websites
http://www.brit-thoracic.org.uk /
http://www.cancernews.com/category.asp?cat=12
http://ats.ctsnetjournals.org /
http://www.surg.med.utoronto.ca/thor /
http://www.emedicine.com/radio/topic688.htm
http://medpics.findlaw.com/generateexhibit.php
http://animations.3d4medical.com/Thoracic-Vertebra-X-Ray-animation_AN1181.html
http://www.goremedical.com/tag /
http://nsmc.staywellsolutionsonline.com/RelatedItems/87,P08273
http://www.mdevidence.com/generateexhibit.php?ID=7981
http://smartimagebase.org/generateexhibit.php?ID=5054
http://www.indexedvisuals.com/scripts/ivstock/pic.asp?id=601-011
http://centegra.org/Content.asp?PageID=P08258
Siemens Rolls Out 1.5 Tesla MRI for Breast Visualization
Siemens is introducing an MRI machine, called Magnetom Espree-Pink, specifically designed for breast imaging. The 1.5 Tesla device features an innovative Sentinelle Vanguard Siemens' coil, and a 70cm bore size for those who are on the front lines of the obesity epidemic.
From Siemens:
The flexible "Sentinelle Vanguard for Siemens" coil solution makes both imaging and biopsies possible using only a single coil. Depending on requirements, only the lateral inserts of the coil are replaced. The frame itself remains on the table and does not have to be repositioned. In addition, due to its variable coil geometry (VCG), the coil can be optimally adapted to the different breast sizes of various patients. Excellent image quality is attained through an improved signal-to-noise ratio and with the help of eight RF channels.The new system additionally offers a comprehensive range of standard and advanced applications for breast imaging. These include, among others, the Breast Suite with Syngo Views for routine examination requirements, which can be used to obtain a three-dimensional representation of the breast with a high spatial and high temporal resolution in the sub-millimeter range, for instance. Syngo Grace is an application package for quantitative MR breast spectroscopy. This software can display the biomarker choline, thus providing valuable information on the biochemical composition of breast lesions. Syngo Blade is an application that ensures motion-free images, even when the patient moves during the examination.
The workstation of the Magnetom Espree-Pink is equipped with the new syngo BreVis and syngo BreVis Biopsy software applications for planning and running the individual work steps during the image acquisition and biopsy processes. For example, syngo BreVis enables clinicians to prepare reports, calculate the size of a lesion, or compare MRI results with ultrasound or X-ray mammography images. The syngo BreVis Biopsy software application supports the physician in performing biopsies accurately and quickly using automatic calculations and pre-settings.
The system is equipped with 18 channels, which ensures its investment security. The breast scanner can be upgraded to a Magnetom Espree with all imaging possibilities for any anatomical region, if required.
Press release: Innovation for Women's Health - the new MRI breast scanner from Siemens (PDF)
CT-guided Placement of Microcoils Helps with VATS for Lung Nodules
From the press release:
VATS is a minimally invasive technique in which one or more small incisions are made in the patient's chest and a small fiber optic camera and surgical instruments are inserted through the incisions. Images transmitted by the camera guide the physician through the procedure.VATS can replace a traditional thoracotomy, a surgical procedure that uses one larger incision to gain access to the chest. VATS typically results in less pain and faster recovery time for the patient compared to open surgery.
Because small, peripheral lung nodules can be difficult to locate, physicians often have to resort to the more invasive thoracotomy procedure, removing larger amounts of lung tissue to successfully locate small nodules.
For the study, Dr. Mayo and colleagues used CT-guided microcoil placement to assist in VATS removal of 75 small, peripheral lung nodules in 69 patients ranging in age from 31 to 81 years. Four patients had two nodules treated, and two of the patients had second nodules removed at a later date. In all, 75 procedures were performed. The microcoil technique allowed the researchers to locate 100 percent of small nodules, and 97 percent of the lung nodules were successfully and completely removed with VATS.
The results show that with precise microcoil localization, even small nodules can be removed with VATS.
"The real beauty of this procedure is that we are able to remove the entire nodule and very little surrounding tissue, so there is no decrease in lung function," Dr. Mayo said. "Recovery time is significantly reduced in these patients as a result. Instead of the three- to six-week recovery period that follows a thoracotomy, these patients can return to work within two to three days."
Press release: Microcoils Help Locate Small Lung Nodules ...
Surgery and Trauma websites
http://www.nationalasthma.org.au/html/management/spiro_book
http://www.trauma.org/index.php/main/moulages /
http://www.vesalius.com /
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http://www.dartmouth.edu/~anatomy/Intro-to-radiology/index.htm
http://rad.usuhs.mil/rad/chest_review/index.html
http://rad.usuhs.edu/medpix/medpix_home.html
http://student.bmj.com/back_issues/1200/education/444.html
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http://www.brighamrad.harvard.edu/education.html
http://rad.usuhs.mil/rad/chest_review/index.html
http://www.radiologyeducation.com/
http://student.bmj.com/topics/clinical/imaging_techniques.php
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http://www.aap.org /
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http://www.hawaii.edu/medicine/pediatrics/pedtext/pedtext.html
http://www.cdc.gov/growthcharts /
http://meded-portal.ucsd.edu/isp/2001/ped_derm/index.cfm
http://www.drmhijazy.com/english/ebook.htm
http://library.med.utah.edu/pedineurologicexam/html
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http://www.virtualpediatrichospital.org /
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http://www.hawaii.edu/medicine/pediatrics/pedtext/pedtext.html
http://web.archive.org/web/20051230113930/www.vnh.org
http://www.uihealthcare.com/depts/med/pediatrics
RETISERT Eye Implant Prevents Lost Vision
Sympathetic ophthalmia is an autoimmune condition thought to be caused when one eye is severely damaged, and the immune system overreacts and attacks the healthy eye, often leading to complete blindness. Until recently the common treatment option was oral steroids and immunosuppressive medication, but now clinicians at the University of Iowa are using a steroid releasing implant from Bausch & Lomb to prevent such a form of blindness.
University of Iowa reports:
The new Retisert treatment involves the surgical implantation into the endangered eye of a small plastic tab that contains a slow-release steroid called fluocinoloe acetonide. The insert provides immunosuppression only to the endangered eye, not other body parts. It lasts for about two-and-a-half years and then can be replaced.Along with UI retinal surgeons James Folk, M.D., professor of ophthalmology, and Karen Gehrs, M.D., clinical associate professor of ophthalmology, Mahajan published a retrospective paper online in January in the journal Ophthalmology that documents the successful use of Retisert to treat eight patients with sympathetic ophthalmia.
The device previously was studied in approximately 300 individuals who had a different immune system inflammation of the eye. The UI-led sympathetic ophthalmia study found that with Retisert, the eight patients reduced or eliminated use of systemic medications to control inflammation. While two patients needed to resume using an oral immunosuppressive, vision improved or remained stable in all eight patients."Using Retisert, we are stabilizing vision in patients with sympathetic ophthalmia and getting them off the heavy-duty immunosuppressive medications," Mahajan said. "Patients had been willing to put up with the serious side effects of systemic immunosuppression because if they lost vision in their remaining good eye, it would be totally life-altering. With Retisert, we can save the eye, and the side effects are limited to treatable risks of high pressure or cataracts in the eye."
While each implant costs approximately $20,000, their use appears to be less expensive over the long run compared to systemic immunosuppressive drugs and the required frequent hospital visits.
"If you add up the total number of patient visits, costs of lab tests and the costs of the immunosuppressive drugs, the $20,000 for the device is cheaper," Mahajan said.
Press release: New surgical implant tested at UI prevents total blindness
Product page: RETISERT
Pharmacology websites
http://www.fda.gov/cder/da/da.htm #
http://www.pharmacology2000.com/General/Pharmacokinetics
http://www.rxlist.com/script/main/hp.asp
http://www.gcrweb.com/HeartDSS/phadiur.htm
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http://www.accp1.org /
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http://www.pharmamotion.com.ar/index.html
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http://pathweb.uchc.edu /
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http://www.ascp.org/general/pub_reso...athologist.asp
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http://www.aamc.org/students/cim/pub_pathology.htm
http://www.apcprods.org/recruit.ppt
http://www.apcprods.org/aboutpath.html
http://pathologyoutlines.com /
http://www.surgicalpathologyatlas.com/db /
http://pathology2.jhu.edu/gicases /
http://www.pathguy.com /
http://tpis.upmc.com/TPIShome /
http://nih.techriver.net /
http://pathology2.jhu.edu/sp /
http://www.endometrium.org/index.htm
http://www.pathmd.com /
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Ophthalmology websites
http://www.aao.org /
http://www.redatlas.org/main.htm
http://www.eyeatlas.com/contents.htm
http://www.nyee.edu/page_deliv.html?page_no=50
http://www.nei.nih.gov/photo /
http://eyelearn.med.utoronto.ca /
http://www.eyeandear.org.au/training/EYE_medstudents.asp
http://cim.ucdavis.edu/EyeRelease/Interface/eSim.htm
http://www.djo.harvard.edu/
http://www.eyecancer.com /
http://www.atlasophthalmology.com/design/3 /
http://www.nei.nih.gov/index.asp
http://www.eyeworld.org /
http://www.eyesite.ca/english/index.htm
http://dro.hs.columbia.edu/
http://www.eyeatlas.com/Eyeatlas/Home.html
http://www.nyee.edu/page_deliv.html?page_no=50
http://www.bordeninstitute.army.mil/published_volumes
http://www.lib.uiowa.edu/hardin/md/ophth.html
Revolution Medical's Retractable Safety Syringe Gets FDA OK
Revolution Medical's Retractable Safety Syringe Gets FDA OK
Revolution Medical, a small firm out of Mount Pleasant, South Carolina, won FDA approval to market the firm's innovative safety syringe. The unit develops a vacuum inside the chamber as the plunger is depressed. When it reaches the end, the needle breaks through the plunger's membrane and gets sucked into the chamber. Watch the video at the product link below to see it in action.
Advantages of the Rev Vac syringe according to Revolution Medical:
No splatter or aerosol. Actuation requires less than 1 lb of force. No danger of tissue trauma. Low cost. Fewer needle sticks. Simple and intuitive to use. No instructions needed The needle is retracted directly from the patient into the barrel of the syringe. The needle safely and automatically retracts into the barrel Graduation lines are easy to read. Hands and fingers stay behind the front of the syringe. Lower disposal costs. It takes up less room in sharps containers.
Product page with video demonstrating the mechanism of the syringe....
Press release: Revolutions Medical Receives 510K FDA Clearance To Market Rev Vac Safety Syringe ...
Oncology and Hematology websites
http://www.merck.com/mmpe/sec11.html
http://asheducationbook.hematologylibrary.org/current.shtml
http://www.nccn.org/professionals/physician_gls/f_guidelines.asp?button=I+Agree
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Greys Anatomy - Season 4 Episode 9[Crash Into Me (Part 1)]
Summary
Meredith and the Chief rush to the scene of a devastating ambulance crash in which the lives of the paramedics are at stake. Bailey treats a difficult patient and Ava returns to find Alex with a new girlfriend.
Greys Anatomy - Season 4 Episode 14[The Becoming]
Summary
The nurses' outcry over McSteamy's frequent trysts leads the hospital to enact a new "date and tell" policy. Meanwhile, news about Burke's career force Cristina to cope with her feelings about the past; Meredith and Derek take in a veteran soldier to participate in their clinical trial; and Callie finds comfort in Sloane when she needs it the most.
Greys Anatomy - Season 4 Episode 17[Freedom (2)]
Summary
In the two-part season finale, Meredith and Derek take another shot at the clinical trial while the others race to free a boy from a hardening block of cement. Meanwhile, Izzie helps Alex care for Rebecca and Lexie learns a secret about George's intern status.
Greys Anatomy - Season 4 Episode 1[A Change Is Gonna Come]
Summary
Meredith and Cristina return from Cristina's honeymoon to find that Burke is long gone. Izzie, Alex, Meredith and Cristina start their first day as residents, each with their own set of interns. Among the interns are George, who is repeating his internship after failing the exam, and Lexie, Meredith's half-sister. Meanwhile, Derek begins to look elsewhere after his relationship with Meredith hits an emotional impasse; Bailey grapples with the fact that her former interns now report to Callie, the new Chief Resident; and Richard returns to his position as Chief of Surgery.
Greys Anatomy - Season 4 Episode 3[Let the Truth Sting]
Summary
The new interns are in awe of fellow intern George's skill level, and Lexie tries to keep his "repeater" status secret. Meredith comes to Lexie's aide when Lexie is faced with her first emergency situation. The Chief and Sloan have to use a radical surgery to save a woman's vocal ability. Meanwhile, George debates telling Callie about his affair with Izzie.
Greys Anatomy - Season 4 Episode 2[Love/Addiction]
Summary
The interns and residents treat victims of an apartment complex explosion as Alex looks into the cause of the devastating accident. Mama Burke arrives at Seattle Grace to pick up the rest of Burke's personal things while Cristina trades wedding gifts for surgeries. Meanwhile, Lexie tries to talk to Meredith, who is less than willing to do so; Callie deals with the stress of being Chief Resident; and Bailey tries to figure out what to do with her excess leadership skills.
Greys Anatomy - Season 4 Episode 4[The Heart Of The Matter]
Summary
Izzie reveals her true feelings for George to one of her and George's friends, and the reaction she receives is not what she expected. Meanwhile, Adele Webber rushes her niece to Seattle Grace; Derek gives Cristina pointers on how to be a better teaching resident; and Norman, the world's oldest intern, misdiagnoses Meredith's patient.
Greys Anatomy - Season 4 Episode 8[Forever Young]
Summary
The ER is thrown into a state of chaos following a school bus accident. Meanwhile, Bailey treats her high school crush; Derek goes on a date; and Thatcher comes to Seattle Grace in search of Meredith.
Greys Anatomy - Season 3 Episode 22[The Other Side of This Life (1)]
Summary
Addison, on leave from Seattle Grace, heads to Los Angeles to reconnect with old friends from med school. Back in Seattle, Meredith continues to bond with Susan, her step-mother, and Cristina, with the help of both her mother and Burke's mother, begins planning her wedding. Meanwhile, Derek performs emergency surgery on Ava (Jane Doe) and Alex continues to stand by her.
Greys Anatomy - Season 3 Episode 23[The Other Side of This Life (2)]
Summary
In the conclusion to part 1, Addison visits Los Angeles and continues to reconnect with her old medical school friends. In Seattle, Meredith gets closer to her step mother. Cristina deals with the pressures of her pending marriage, and reluctantly plans the wedding with her mother and future mother-in-law. Meanwhile, Derek operates on Ava.
Greys Anatomy - Season 3 Episode 24[Testing 1-2-3]
Summary
The interns face one of their biggest challenges yet -- their first-year medical exams. Meanwhile, the interns must tend to three injured mountain climbers. Elsewhere, Callie becomes increasingly suspicious of George and Izzie and Cristina has trouble writing her vows.
Greys Anatomy - Season 3 Episode 25[Didn't We Almost Have It All]
Summary
A big day arrives for all -- Cristina and Burke's wedding and the interns receive their exam results. Meanwhile, Chief Webber's replacement is named and George and Callie make a decision about their relationship.
Greys Anatomy - Season 4 Episode 5[Haunt You Every Day]
Summary
It's Halloween at Seattle Grace and the day is chock-full of surprises for the doctors. Alex has a surprise visit from a former patient; Meredith thinks her mother's ashes are haunting her; Cristina is snubbed by a top surgeon; and everyone is shocked when Callie reveals George and Izzie's relationship to the public.
Greys Anatomy - Season 4 Episode 7[Physical Attraction... Chemical Reaction]
Summary
George and Izzie's relationship is tested, as is Derek and Meredith's when Derek wants more than a physical relationship with her. Meanwhile, Mark falls for a surgeon and Callie's position as Chief Resident is put on the line when she gives too many duties to Bailey.
Greys Anatomy - Season 4 Episode 6[Kung Fu Fighting]
Summary
With his marriage once again falling apart, Chief Webber invites the male surgeons out on a "gentleman's evening." Meanwhile, Cristina and Izzie compete for the same surgeries, mainly to impress the doctor performing them; Meredith treats the survivor of a skydiving accident; and two finalists competing in a promotional competition are treated by the doctors.
Greys Anatomy - Season 3 Episode 15[Walk On Water (1)]
Summary
A horrific ferry boat accident challenges the interns, as well as the rest of the hospital staff, both physically and mentally as they all near their breaking point. Chief Webber has to assemble and send out a team to the location of the accident to help save the few lives that were spared. On location, Alex tends to a woman who was crushed by a cement pylon. Meanwhile, Meredith looks out for a lost young girl and George searches frantically for a woman's young son.
Greys Anatomy - Season 3 Episode 16[Drowning on Dry Land (2)]
Summary
As the chaos surrounding the ferry boat accident continues, Derek frantically searches for Meredith, and is devastated when he finds her barely clinging to life. Cristina is also devastated when she learns about Meredith's condition. Meanwhile, emotions run high at Seattle Grace as family of the accident victims demand to know the status of their loved ones. In the midst of the trauma, Alex has trouble dealing with the death surrounding him; George searches for a missing 7 year-old boy; and Izzie is forced to take desperate measures to save the life of the man stuck under a car.
Greys Anatomy - Season 3 Episode 17[Some Kind of Miracle (3)]
Summary
While Meredith's life hangs in the balance, the interns each have to grapple with the reality that she may not make it. Derek refuses to give up hope that Meredith will pull through, but as time passes, Derek begins to slowly break down. Cristina takes the possibility of her death the hardest, and refuses to accept that it could happen. As Bailey and Chief Webber work to save Meredith's life, Meredith is visited by figures from her past, including Denny and Dylan Young, both of whom try to convince her not to die. Elsewhere, Addison and Alex continue to work with their pregnant Jane Doe, who has no memory of the ferry boat accident or her life prior it.
Greys Anatomy - Season 3 Episode 18[Scars and Souvenirs]
Summary
The race for Chief of Surgery continues to heat up, especially when a new contender enters the race. Callie reveals a big secret to George, and when George ends up telling Meredith, Callie kicks him out, leaving George with no where to go except to Meredith's. Cristina and Burke's engagement suffers when a secret about one of Cristina's past relationships is revealed. Meanwhile, Derek treats an old friend; Alex and Jane Doe get closer; and Meredith has dinner with her father and step-mother.
Greys Anatomy - Season 3 Episode 19[My Favorite Mistake]
Summary
George comes face-to-face with his father-in-law, but the circumstances of their meeting are less than perfect. Alex continues to tend to Jane Doe and helps her choose how the world will see her from here on. Meanwhile, the board interviews Chief of Surgery candidates, and everyone is stunned when Sloan emerges as a top candidate. Elsewhere, Izzie wrestles with the events of her drunken night with George.
Greys Anatomy - Season 3 Episode 20[Time After Time]
Summary
When Izzie has to face her past, she turns to George for support and comfort. As Alex continues to work with Jane Doe, the two become more attached to each other. Meanwhile, Meredith and Derek begin to question their status while Cristina strives to repair her relationship with Burke despite her past history with Dr. Marlow that continues to damage their engagement.
Greys Anatomy - Season 3 Episode 21[Desire]
Summary
As the interns study for and stress over their upcoming exam, the attendings suck up to the chairman of the board in order to become front runner for the Chief's position when he is admitted to the hospital as a patient. Meanwhile, Burke has a difficult time involving Cristina in the planning of their wedding, Addison and Alex get closer, and Derek begins to second guess his relationship with Meredith.
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